P146 Report There are no comments up to now.
| Uganda, Project 146, 2006 - 2010 |
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Evidence-based malaria interventions in a conflict zone in Northern Uganda
The St. Mary´s Hospital Lacor lies in the North of Uganda, about 4 km away from Gulu, close to the Sudanese-Ugandan border. During the riots over the past decades, it has been the only functioning and continuously accessible structure within the region. Attached to the hospital there are health stations in two refugee camps with 60,000 people each (Opit, Pado). On the basis of local experiences, it can be said that malaria is one of the main causes for diseases, especially for children, and that there are reasons to believe that the blood parasite Plasmodium falciparum has already developed a resistance against the currently practiced combination of therapies. In the context of the project, a sustainable improvement of the therapeutic and diagnostic possibilities will enable an analysis of the parasite's degree of resistance against common medications. This is meant to lead to a substantial reduction of the use of malaria chemotherapeutics and thus relieve the hospital's budget. Furthermore, the limitation of use to microscopically safe cases aims at slowing down the development of resistances and thus diminishing the mortality due to malaria. The project aims are: 1. Survey of the current resistances of Plasmodium falciparum against common chemotherapeutics by means of parallel in vivo and in vitro tests; acquisition of clear statements about the degree of the current resistance situation, clarification of the interaction of acquired immunity and visualization of alternative therapeutic options. 2. Sustainable improvement of diagnostic and therapeutic possibilities in the attached health institutions 3. Creation of a basis for further collaboration between the involved institutions and organizations with regard to follow-up projects
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